Re-excision in breast cancer patients with lobular carcinoma in situ at the final surgical margins

 

 

 

 

 

 

We reviewed 2358 patient records to assess the impact of the presence of Lobular Carcinoma In-Situ (LCIS) at the surgical margins after the final breast-conserving surgery on local control. All patients underwent lumpectomy and breast radiation.
Our study did not find a statistically significant increase in loco-regional recurrence with the presence of LCIS-positive/close surgical margins in patients treated for invasive cancer with breast conserving surgery and radiation therapy. Therefore, our data suggest that LCIS-positive/close surgical margins after lumpectomy are not an indication for surgical re-excision or mastectomy

 

 

 

 

Bibliographic Reference:

Sadek BT et al.: "Risk of Local Failure in Breast Cancer Patients With Lobular Carcinoma In Situ at the Final Surgical Margins: Is Re-excision Necessary?", Int J Radiat Oncol Biol Phys. 2013 Sep 21[Epub ahead of print]

 

 

 

 

Betro Sadek
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA


 

 

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