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Risk for stomach cancer after radiation therapy for cervical cancer
We
conducted a case-control study of 201 cases and 378 controls among
53,547 5-year survivors of cervical cancer diagnosed from 1943 to 1995. More than 90% of women received radiation therapy, mostly
with external beam therapy in combination with brachytherapy. We
estimated individual radiation doses to the site of the stomach cancer
for all cases and to corresponding sites for the matched controls.
Our
study showed for the first time a significant linear radiation
dose-response relationship for risk of stomach cancer in long-term
survivors of cervical cancer.
Bibliographic Reference:
Ruth A. Kleinerman Division of Cancer Epidemiology
and Genetics, National Cancer Institute, Bethesda, MD, USA
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