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A new procedure for noninvasive
detection of breast cancer lymph node metastasis
Using
two cell surface markers found to be highly expressed in breast cancer lymph
node metastases, our team, which included colleagues at University
of
Florida and
Arizona, developed targeted, fluorescent molecular imaging probes that can
non-invasively detect breast cancer lymph node metastases. The new procedure
could spare breast cancer patients invasive and unreliable sentinel lymph
node biopsies and surgery-associated negative side effects.
Bibliographic Reference:
Tafreshi
NK et al.: "Noninvasive Detection of Breast Cancer Lymph Node
Metastasis Using Carbonic Anhydrases IX and XII Targeted Imaging Probes",
Clin
Cancer Res. 2012 Jan 1;18(1):207-19
Narges
Tafreshi
Department
of Molecular and Functional Imaging, H. Lee Moffitt Cancer Center &
Research Institute, Tampa, FL, USA
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