Editor-in-Chief: Gian Paolo Andreoletti, MD

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Literature Selection

• Simoes PW et al.: "Prevalence of Human Papillomavirus in Breast Cancer: A Systematic Review", Int J Gynecol Cancer. 2011 Dec 30. [Epub ahead of print]
• Masala G et al.: "Fruit and vegetables consumption and breast cancer risk: the EPIC Italy study", Breast Cancer Res Treat. 2012 Jan 4. [Epub ahead of print]
• Raftery J et al.:"Possible net harms of breast cancer screening: updated modelling of Forrest report", BMJ. 2011 Dec 8;343:d7627. doi: 10.1136/bmj.d7627
• Scaranelo AM et al.: "Accuracy of Unenhanced MR Imaging in the Detection of Axillary Lymph Node Metastasis: Study of Reproducibility and Reliability", Radiology 2011; Dec 5  [Epub ahead of print]
• Baselga J et al.: "Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer", N Engl J Med. 2011 Dec 7. [Epub ahead of print]
• Huber C et al.: "Anti-estrogen therapy for breast cancer modifies the risk of subsequent cutaneous melanoma", Cancer Prev Res (Phila). 2012 Jan 5; 82
• Gianni L et al.: "Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial", Lancet Oncol. 2011 Dec 6. [Epub ahead of print]
• Baselga J et al.: "Everolimus in Postmenopausal Hormone-Receptor-Positive Advanced Breast Cancer", N Engl J Med. 2011 Dec 7. [Epub ahead of print]
• Hille U et al.: "Aromatase Inhibitors as Solely Treatment in Postmenopausal Breast Cancer Patients", Breast J. 2011 Dec 16 [Epub ahead of print]
• Phillips KM et al.: "Cognitive functioning after cancer treatment: A 3-year longitudinal comparison of breast cancer survivors treated with chemotherapy or radiation and noncancer controls", Cancer. 2011 Dec 12. doi: 10.1002/cncr.26432. [Epub ahead of print]
• Deprez S et al.: "Longitudinal Assessment of Chemotherapy-Induced Structural Changes in Cerebral White Matter and Its Correlation With Impaired Cognitive Functioning", J Clin Oncol. 2011 Dec 19. [Epub ahead of print]
• Nilsson G et al.: "Distribution of Coronary Artery Stenosis After Radiation for Breast Cancer", Clin Oncol. 2011 Dec 27. [Epub ahead of print]
• Bower JE et al.: "Yoga for persistent fatigue in breast cancer survivors: A randomized controlled trial", Cancer. 2011 Dec 16 [Epub ahead of print]

Comment

• "New onco-plastic surgery technique for early breast cancer", Domenico Gerbasi, Unità di Senologia, Ospedale Bolognini, Seriate, Italy
   
  ""Recent advances of oncoplastic techniques in breast surgery have allowed to achieve maximum oncological radicality, together with minor cosmetic alteration possible. This has resulted in an important advantage for the patients subjected to conservative surgery for breast cancer, as proven by many scientific studies that have highlighted in these cases a minor psychological impactl overall. The surgical technique proposed demonstrates that, according to the conventional protocols of breast conserving therapy for cancer, it is possible to perform a complete excision of the tumor, with an "extra-mammary" surgical approach trough an incision made immediately below the inframammary fold, with a scar completely invisible on standing by natural ptosis of the breast. This technique is indicated for cases of early breast cancer, regardless of the location of the tumor, as long as there is no involvement of the overlying skin. Additional research needs to be conducted to evaluate long term results and effectiveness of the proposed technique in relation to a large number of cases"
  (Comment on:  Gerbasi D et al.: "Inframammary fold approach in breast conserving surgery for cancer", Updates Surg. 2011 Dec;63(4):283-6)

Discussion

•   - Radiation Therapy for Breast Cancer: American Society of Breast Surgeons responds to San Antonio Breast Cancer Symposium Data. What do you think? - Share your opinion on  LinkedIn®

Healthcare Companies News

• 2011 CTRC-AACR San Antonio Breast Cancer Symposium: Positive Study Results Validating Use of Oncotype DX(R) in DCIS Breast Cancer - Genomic Health

Calendar of Events

• Implications of a multigene assay for DcIS on current treatment patterns - e-oncoreview, January 17, 2012
• The World Cancer Immunotherapy Conference, January 25-26, 2012, San Diego, CA
• 2nd International Congress of Breast Disease Centers, February 9-10. 2012, Paris, France

Fragments of History

• William S Halsted  (New York, 1852-1922),  "The results of radical operations  for the cure of carcinoma of the breast", Ann Surg. July 1907:46(1):1-19: “I am not sure that I have observed from breast cancer, metastasis which seemed definitely to have been conveyed by way of the blood-vessels (…).We believe that cancer of the breast in spreading centrifugally preserves in the main continuity with the original growth, and before involving the viscera may become widely diffused along surface planes."  

Literature Selection

• Signorello LB et al.: "Congenital Anomalies in the Children of Cancer Survivors: A Report From the Childhood Cancer Survivor Study", J Clin Oncol. 2011 Dec 12. [Epub ahead of print]
• Schroeder S et al.: "Acupuncture for chemotherapy-induced peripheral neuropathy (CIPN): a pilot study using neurography", Acupunct Med. 2011 Dec 5. [Epub ahead of print]
• Rijkaart DC et al.: "Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer: final results of the POBASCAM randomised controlled trial", Lancet Oncol. 2011 Dec 14. [Epub ahead of print]
• Popadich A et al.:"A multicenter cohort study of total thyroidectomy and routine central lymph node dissection for cN0 papillary thyroid cancer", Surgery. 2011 Dec;150(6):1048-57
• Trinchet JC et al.: "Ultrasonographic surveillance of hepatocellular carcinoma in cirrhosis: A randomized trial comparing 3- and 6-month periodicities", Hepatology. 2011 Dec;54(6):1987-1997
• Nishikawa H et al.: "Comparison of percutaneous radiofrequency thermal ablation and surgical resection for small hepatocellular carcinoma", BMC Gastroenterol. 2011 Dec 28;11(1):143. [Epub ahead of print]
• Simon MS et al.: "Prospective analysis of association between use of statins or other lipid-lowering agents and colorectal cancer risk", Ann Epidemiol. 2012 Jan;22(1):17-27
• Meyer RM et al.: "ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's Lymphoma", N Engl J Med. 2011 Dec 11. [Epub ahead of print]
• Jensen AO et al.: "Atopic dermatitis and risk of skin cancer: a danish nationwide cohort study (1977-2006)", Am J Clin Dermatol. 2012 Feb 1;13(1):29-36
• Barry MJ et al.: "Adverse Effects of Robotic-Assisted Laparoscopic Versus Open Retropubic Radical Prostatectomy Among a Nationwide Random Sample of Medicare-Age Men", J Clin Oncol. 2012 Jan 3. [Epub ahead of print]
• Nguyen PL et al.: "Association of androgen deprivation therapy with cardiovascular death in patients with prostate cancer: a meta-analysis of randomized trials", JAMA. 2011 Dec 7;306(21):2359-66
• Andriole GL et al.: "Prostate Cancer Screening in the Randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: Mortality Results after 13 Years of Follow-up", J Natl Cancer Inst. 2012 Jan 6. [Epub ahead of print]
• Dearnaley D et al.: "Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: preliminary safety results from the CHHiP randomised controlled trial", Lancet Oncol. 2011 Dec 12. [Epub ahead of print]