Editor-in-Chief: Gian Paolo Andreoletti, MD

Join us on  LinkedIn, Twitter, Facebook, ResearchGate, Doctorsbook, Google Groups, YouTube, SlideShare, Flickr, and share informations and opinions.  Read the Senology.org Newspaperdaily

 

Literature Selection

• Skaane P et al.: "Comparison of Digital Mammography Alone and Digital Mammography Plus Tomosynthesis in a Population-based Screening Program", Radiology. 2013 Jan 7. [Epub ahead of print]
• Marinovich ML et al.: "Meta-analysis of Magnetic Resonance Imaging in Detecting Residual Breast Cancer After Neoadjuvant Therapy", J Natl Cancer Inst. 2013 Jan 7. [Epub ahead of print]
• Magbanua MJ et al.: "Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients", Cancer Res. 2013 Jan 1;73(1):30-40
• Wallwiener M et al.: "The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer", Breast Cancer Res Treat. 2013 Jan;137(2):503-10
• Zhu Q et al.: "Breast Cancer: Assessing Response to Neoadjuvant Chemotherapy by Using US-guided Near-Infrared Tomography", Radiology. 2012 Dec 21. [Epub ahead of print]
• Goss PE et al.: "Adjuvant lapatinib for women with early-stage HER2-positive breast cancer: a randomised, controlled, phase 3 trial", Lancet Oncol. 2012 Dec 7 [Epub ahead of print]
• Prat A et al.: "Prognostic Significance of Progesterone Receptor-Positive Tumor Cells Within Immunohistochemically Defined Luminal A Breast Cancer", J Clin Oncol. 2012 Dec 17. [Epub ahead of print]
• Zhang X et al.: "Postmenopausal plasma sex hormone levels and breast cancer risk over 20 years of follow-up", Breast Cancer Res Treat. 2013 Jan 3. [Epub ahead of print]
• Eliassen AH et al.: "Circulating Carotenoids and Risk of Breast Cancer: Pooled Analysis of Eight Prospective Studies", J Natl Cancer Inst. 2012 Dec 6. [Epub ahead of print]

Comment

• "Antiviral therapy should be used in patients with HBV-related hepatocellular carcinoma after curative resection" - Chun-Ying Wu, School of Medicine, National Yang-Ming University, Taipei, Taiwan

  "Tumor recurrence is a major issue for patients with hepatocellular carcinoma (HCC) following curative liver resection. In the present study, we found antiviral agents can reduce one-third HBV-related HCC tumor recurrence after curative liver resection for hepatitis B virus (HBV)-related HCC patients,. Based on 100,983 HCC patients in the Taiwan's nationwide database, we identified 518 HBV-related HCC patients receiving nucleoside analogues and 4051 untreated HBV-related HCC patients.  After adjusting competing mortality, we found the treated group had significantly reduced 6-year HCC recurrence rate and overall mortality rate. We recommend antiviral therapy should be used in HBV-related HCC patients after curative resection".
  (Commentary on:  Wu CY et al.: "Association between nucleoside analogues and risk of hepatitis B virus–related hepatocellular carcinoma recurrence following liver resection", JAMA. 2012 Nov 14;308(18):1906-14)

Discussion

•   "Breast cancer screening: significant increase in cancer detection rates and decrease in false-positive rates with mammography plus tomosynthesis compared with mammography alone " - Share your opinion on LinkedIn

Questions and Answers 

• Breast Cancer Workshop Summary - with Gabriel Hortobagyi, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Calendar of Events

• Breast-Gynecological International Cancer Congress, January 17-18, 2013, Cairo, Egypt
• 13th St. Gallen International Breast Cancer Conference, March 13-16, 2013, St. Gallen, Switzerland
• 5th IMPAKT Breast Cancer Conference, May 2-4, 2013, Brussels, Belgium

Literature Selection

• Wand HM et al.: "Improved survival outcomes with the incidental use of beta-blockers among patients with non-small-cell lung cancer treated with definitive radiation therapy", Ann Oncol. 2013 Jan 8. [Epub ahead of print]
• Lindgren ME et al.: "Beta-blockers may reduce intrusive thoughts in newly diagnosed cancer patients", Psychooncology. 2012 Dec 17 [Epub ahead of print]
• Francica G et al.: "Long-term effectiveness of Radiofrequency Ablation for solitary small Hepatocellular Carcinoma: A retrospective analysis of 363 patients", Dig Liver Dis. 2012 Dec 12 [Epub ahead of print]
• Hosaka T et al.: "Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection", Hepatology. 2012 Dec 5 [Epub ahead of print]
• Bao Y et al.: "A Prospective Study of Plasma Adiponectin and Pancreatic Cancer Risk in Five US Cohorts", J Natl Cancer Inst. 2012 Dec 14. [Epub ahead of print]
• Pence BC et al.: "Combination aspirin and/or calcium chemoprevention with colonoscopy in colorectal cancer prevention: cost-effectiveness analysis", Cancer Epidemiol Biomarkers Prev. 2012 Dec 18. [Epub ahead of print]
• Thosani N et al.: "Reduced Risk of Colorectal Cancer With Use of Oral Bisphosphonates: A Systematic Review and Meta-Analysis", J Clin Oncol. 2012 Dec 26. [Epub ahead of print]
• Isham CR et al.: "Pazopanib enhances Paclitaxel-induced mitotic catastrophe in anaplastic thyroid cancer", Sci Transl Med. 2013 Jan 2;5(166):166ra3
• Kinde I et al.: "Evaluation of DNA from the papanicolaou test to detect ovarian and endometrial cancers", Sci Transl Med. 2013 Jan 9;5(167):167ra4

Questions and Answers 

• Leukemia Workshop Summary - with Jorge Cortes, The University of Texas MD Anderson Cancer Center, Houston, TX, USA  
• Bladder Cancer Workshop Summary - with Steven Wong,  UCLA School of Medicine, Los Angeles, CA, USA
• Pediatric Neuro-Oncology Workshop Summary - with Adam Levy, Children's Hospital at Montefiore, New York, NY, USA
• Palliative Care Workshop Summary - with Thomas Smith, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
• Melanoma Workshop Summary - with David Fisher, Massachusetts General Hospital, Boston, MA, USA

Fragments of History

• Sidney Farber (1903–1973) showed for the first time in 1948 that folic acid antagonists could induce temporary remission in childhood leukemia (Farber S et al.: “Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-amino-pteroyl-glutamic acid (aminopterin)”, N Engl J Med 1948;238:787-793)  

Literature Selection

• Gupta J et al.: "Levonorgestrel intrauterine system versus medical therapy for menorrhagia, N Engl J Med. 2013 Jan 10;368(2):128-37