"Is breast-conserving surgery followed by
radiotherapy better than mastectomy for patients with
triple-negative breast cancer?" - Share
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"A
previous study showed an incremental cancer detection rate of
about 30% by adding routine ultrasonography in subjects with
negativa mammography and dense breast. Still such an increase in
detection might not be necessarily a benefit, e.g., it might
account for overdiagnosis of not aggressive tumors. This study
analyses the frequency of interval cancer in non-dense breast
screened by mammography and in dense breasts screened by
mammography + ultrasonography. In theory one would expect more
interval cancers in dense breasts, as density reduces
mammography sensitivity due to a masking effect. The finding of
a similar (higher over age 50) frequency of interval cancers in
dense as compared to non-dense breast is a convincing prove that
ultrasonography really improves the sensitivity of mammography
by reducing its false negatives" (Comment
on: Corsetti
V et al.: "Evidence of the effect of adjunct ultrasound
screening in women with mammography negative dense breasts:
Interval breast cancers at 1year follow-up", Eur
J Cancer. 2011:47(7): 1021-6)
Fragments of History
Charles H. Moore:, Royal Medical and
Chirugical Society, London, 1867: “On
the influence of inadequate operations on the theory of cancer",
Med Chir Trans 32: 245-80:
“It
is not sufficient to remove the cancer or any
portion only of the breast in which it is situated; mammary
cancer requires the careful extirpation of the entire organ. It
is desirable to avoid not only cutting into the tumor but also
seeing it. No actually morbid texture should be exposed, lest the active microscopic elements in it
should be set free and lodge in the wound. Diseased axillary
glands should be taken away at the same dissection as the breast
itsel"
