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Official website of the International Senology Oncology Scientific Community

 

 

 

Editor-in-chief: Dr. Gian Paolo Andreoletti - Oncologist, Science Journalist

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 



Gastrointestinal and Pancreatic Cancers

 

 

 

 

 

LINKS 

 

M.D. Anderson Cancer Center: Colorectal cancer 

 

 M.D. Anderson Cancer Center: Stomach cancer    

 

M.D. Anderson Cancer Center: Esophageal cancer   

 

M.D. Anderson Cancer Center: Pancreatic cancer   

 

Memorial Sloan-Kettering Cancer Center: Colorectal cancer 

 

Memorial Sloan-Kettering Cancer Center: Gastric cancer   

 

Memorial Sloan-Kettering Cancer Center: Esophageal cancer 

 

Memorial Sloan-Kettering Cancer Center: Pancreatic cancer    

 

National Cancer Institute: Colorectal cancer 

 

National Cancer Institute: Pancreatic Cancer 

 

The New England Journal of Medicine Collections: Colorectal cancer 

 

British Medical Journal Collections: Gastroenterological cancers   

 

Medscape Resource Centers: Colorectal cancer   

 

The Journal of  the American Medical Association Collections: Colon cancer    

 

Clinical Colorectal Cancer  

 

Gastric Cancer 

 

   

 

LITERATURE SELECTION

 

 

 

 

Smalley SR et al.: "Updated Analysis of SWOG-Directed Intergroup Study 0116: A Phase III Trial of Adjuvant Radiochemotherapy Versus Observation After Curative Gastric Cancer Resection", J Clin Oncol. 2012 May 14. [Epub ahead of print]

 

 

Holdenrieder S et al.: "Cytokeratin serum biomarkers in patients with colorectal cancer", Anticancer Res. 2012 May;32(5):1971-6

 

 

Sanoff HK et al.: "Effect of Adjuvant Chemotherapy on Survival of Patients With Stage III Colon Cancer Diagnosed After Age 75 Years", J Clin Oncol. 2012 Jun 4. [Epub ahead of print]

 

 

Wu S et al.: "Fish Consumption and Colorectal Cancer Risk in Humans: A Systematic Review and Meta-analysis", Am J Med. 2012 Jun;125(6):551-559.e5

 

Kang SY et al.: "Helicobacter pylori infection as an independent prognostic factor for locally advanced gastric cancer patients treated with adjuvant chemotherapy after curative resection", Int J Cancer. 2011 Mar 21. doi: 10.1002/ijc.26081. [Epub ahead of print]

 

Chan AT et al.: "Inflammatory markers are associated with risk of colorectal cancer and chemopreventive response to anti-inflammatory drugs", Gastroenterology. 2011 Mar;140(3):799-808.e2

 

 

 

 

 

 

CLINICAL GUIDELINES

 

 

 

" Endoscopic submucosal dissection (ESD) of oesophageal dysplasia and neoplasia: guidance " - NICE - National Institute For Clinical Excellence, London, UK - www.nice.org.uk

 

"Capecitabine for the treatment of advanced gastric cancer" - NICE - National Institute For Clinical Excellence, London, UK - www.nice.org.uk  

 

"Epithelial radiofrequency ablation for Barrett's oesophagus" -  NICE - National Institute For Clinical Excellence, London, UK - www.nice.org.uk 

 

"Endoscopic submucosal dissection of lower gastrointestinal lesions" -  NICE - National Institute For Clinical Excellence, London, UK - www.nice.org.uk

 

"NCCN Updates Colorectal Screening Guidelines to Include Additional Primary Screening Modality" - The National Comprehensive Cancer Network, USA - www.nccn.org

 

"Colorectal cancer (first line) - cetuximab: full guideline" - NICE - National Institute For Clinical Excellence, London, UK - www.nice.org.uk

 

"NCCN Announces Updates to Pancreatic Adenocarcinoma Guidelines" - The National Comprehensive Cancer Network, USA - www.nccn.org

 

Rex DK et al.: "American college of gastroenterology guidelines for colorectal cancer screening 2008", Am J Gastroenterol. 2009 Mar;104(3):739-50

 

"Circumferential epithelial radiofrequency ablation for Barrett's oesophagus" - NICE - National Institute For Clinical Excellence, London, UK, www.nice.org.uk

 

 

 

 

PRESS RELEASES

 

 

"Multivitamin use doesn't impact colon cancer outcomes, study finds", Dana-Farber Cancer Institute, Boston, MA, USA - www.dana-farber.org  

 

 

"Studies Report Progress Against Genitourinary, Gastrointestinal and Gynecologic Cancers" - American Society of Clinical Oncology (ASCO) - www.asco.org

 

"Criteria Based on Standard CT Imaging Taken Post Avastin-Chemotherapy Regimen May Predict Overall Survival in Patients with Metastatic Colorectal Cancer" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

 

"Regular aspirin use reduces risk of dying from colorectal cancer" - Fred Hutchinson Cancer Research Center, Seattle, WA, USA  - www.fhcrc.org 

 

"New Minimally Invasive Surgery Option for Patients with Stomach Cancer" - Memorial Sloan-Kettering Cancer Center, New York, USA - www.mskcc.org

 

Abnormal DNA Repair Genes May Predict Pancreatic Cancer Risk - M. D. Anderson study identifies gene variants that interact with known factors for the disease / Press release/ The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA  - www.mdanderson.org

 

"NCCN Updates Guidelines for Colorectal Cancer" - National Comprehensive Cancer Network, USA - www.nccn.org 

 

"Gene Variations Alter Risk of Esophageal Cancer" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

 

"New Study Examines Effectiveness of Colorectal Cancer Screening Tests and Suggests Screening May Be Stopped at Age 75" - Memorial Sloan-Kettering Cancer Center, New York, USA - www.mskcc.org

 

Hepatitis B Exposure May Increase Risk For Pancreatic Cancer - Study suggests administering chemotherapy might reactivate liver virus - Press Release / Comunicato Stampa - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

 

"Large, Multi-Center Trial Demonstrates Comparable Accuracy for Virtual Colonoscopy and Standard Colonoscopy" - National Institutes of Health (NIH), U. S. Department of Health and Human Services - www.nih.gov

 

"Calorie Restricted Diet Prevents Pancreatic Inflammation and Cancer" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

 

"Calorie Restriction Limits and Obesity Fuels Development of Epithelial Cancers" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

 

"Red Meat Consumption Linked to Colorectal Cancer" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

 

"Gleevec Decreases Cancer Recurrence for Patients with Primary Gastrointestinal Stromal Tumor" - National Institutes of Health (NIH), U. S. Department of Health and Human Services

"Colon Cancer Survival Linked To Number of Lymph Nodes Examined" - University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA 

 

"Regular, moderate-to-vigorous aerobic exercise significantly reduces markers of increased colon-cancer risk in men" - Fred Hutchinson Cancer Research Center, Seattle, WA, USA

"FDA Approves a New Drug for Colorectal Cancer" - U.S. Food and Drug Administration, Department of Health & Human Services 

 

"Aspirin and Other Nonsteroidal Anti-Inflammatory Drugs May Cut Risk of Esophageal Cancer in People with Barrett's Esophagus" - Fred Hutchinson Cancer Research Center, Seattle, WA

 

"Computer-Aided Polyp Detection Software in Combination with Virtual Colonoscopy is as Effective as Traditional Optical Colonoscopy" - National Institutes of Health (NIH), U. S. Department of Health and Human Services

 

"Regular, moderate-to-vigorous aerobic exercise significantly reduces markers of increased colon-cancer risk in men" - Fred Hutchinson Cancer Research Center, Seattle, WA, USA

 

 

 

 

NEWS  

 

Hormone replacement therapy and distal large bowel cancer - Hormone replacement therapy is associated with a lower risk of distal large bowel cancer - Am J Gastroenterol. 2010 Mar 30. [Epub ahead of print] 

 

Alcohol and pancreatic cancer

Alcohol and pancreatic cancer - Cancer Epidemiology, Biomarkers & Prevention - Alcohol intake is associated with a slight positive association with pancreatic cancer 

 

Hot tea and esophageal cancer

Hot tea and esophageal cancer - BMJ - Hot tea is strongly associated with a higher risk of oesophageal cancer  

 

Coffee consumption and oral, pharyngeal, and esophageal cancers

Coffee consumption and oral, pharyngeal, and esophageal cancers - American Journal of Epidemiology -  Coffee consumption is associated with a lower risk of oral, pharyngeal, and esophageal cancers  

 

Cigarette smoking, H. pylori and gastric cancer

Cigarette smoking, H. pylori and gastric cancer - The American Journal of Epidemiology - H. pylori infection and cigarette smoking are significant risk factors for gastric carcinoma 

 

Aspirin use and colorectal cancer Aspirin use and colorectal cancer - Gastroenterology - Regular long-term aspirin use reduces risk of colorectal carcinoma in men 

 

Colorectal cancer risk and dairy consumption

Colorectal cancer risk and dairy consumption - American Journal of Clinical Nutrition - A diet rich in dairy products during childhood is associated with a greater risk of colorectal carcinoma during adulthood 

 

Serum cholesterol levels and gastric cancer

Serum cholesterol levels and gastric cancer - International Journal of Cancer - Low serum cholesterol levels are an independent risk factor for developing gastric carcinoma 

 

Whole grains and pancreatic cancer

Whole grains and pancreatic cancer - American Journal of Epidemiology - Consuming more whole-grain or high-fiber foods may reduce the risk of pancreatic carcinoma

 

 

 

EDITORIALS

 

 

Inverse association between coffee consumption and the incidence risk of oral, pharyngeal, and esophageal cancers - Toru Naganuma

Influences of cigarette smoking and Helicobacter pylori infection on the development of gastric cancer - Yutaka Kiyohara

Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal surface disease from colorectal cancer - Perry Shen

Computed tomographic colonography and optical colonoscopy for colorectal-cancer screening and prevention - Kim DH

A successful approach for preventing severe and life-threatening toxicities in gastrointestinal cancer patients who are candidates for standard 5-FU treatment - Guido Bocci

Older patients with shorter life expectancies may receive less benefit from colorectal cancer screening - Cary P Gross  

A successful approach for preventing severe and life-threatening toxicities in gastrointestinal cancer patients who are candidates for standard 5-FU treatment - Guido Bocci 

 

 

 

Long-term gastric acid suppression is safe regarding development of oesophageal and gastric adenocarcinoma - Mats Lindblad 

 

 

 

Chemotherapy in advanced colorectal cancer: prolongation of life or quality of life improvement? - Susanne de Kort 

 

 

 

Previous use of carbonated soft drinks and esophageal or cardia adenocarcinoma - Jesper Lagergren

 

 

 

Long term risk of clinically manifest colorectal cancer among patients with negative findings at colonoscopy - Hermann Brenner

 

 

 

Exercise reduces the incidence and mortality of colorectal cancers - Andrew Haydon

 

 

 

Screening colonoscopy in very elderly patients - Otto Lin

 

 

 

Preoperative hyperfractionated and accelerated radiotherapy schedule (HART) in locally advanced resectable rectal cancer (LARC) - Philippe A. Coucke

 

 

 

Patients with hepatic and pulmonary metastases from colorectal cancer may benefit from aggressive surgical therapy - Shimul A. Shah, Steven Gallinger, Alice C. Wei 

 

 

 

Benefits of palliative chemotherapy in patients over the age of 70 with oesophago-gastric cancers - Naureen Starling

 

 

 

The association between C-reactive protein concentrations and development of colon cancer - Kathy J. Helzlsouer 

 

 

 

Management of chronic radiation enteritis - Cecilia Gavazzi

 

 

 

Nodal dissection for gastric cancer patient provides survival benefit when done by well-trained, experienced surgeons in high gastric cancer volume hospital - Chew-Wun Wu

 

 

 

Laparoscopic and open approach in elderly patients with colon or rectal cancer - Andrea Vignali 

 

 

 

 

Lifestyle as a predictor for colorectal cancer in asymptomatic individuals - Inger Kristin Larsen 

 

 

 

 

High-dose radiation with concurrent hepatic arterial floxuridine in patients with unresectable

 intrahepatic malignancies - Edgar Ben-Josef

 

 

 

 

Gastro-esophageal junction adenocarcinoma and endoscopic ultrasonography - Giovanni de Manzoni, Corrado Pedrazzani

 

 

 

A novel peptide vaccine directed against the thymidylate synthase. A rationale combination with 5-FU based chemotherapy - Pierpaolo Correale 

 

 

 

Pre and intraoperative risk factors that potentially influence morbidity and mortality after esophagectomy for esophageal carcinoma - Ines Gockel

 


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